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Daptomycin

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Daptomycin is a semi-synthetic cyclic polypeptide antibiotic that is active against vancomycin-resistant gram-positive bacteria, including enterococci and Staphylococcus aureus. Its bactericidal activities have been attributed to its role in disruption of membrane potential and increased efflux of potassium ions from bacterial cells, which lead to disruption of protein, DNA, and RNA synthesis. Exhibits superior bactericidal properties compared to vancomycin hydrochloride, even in the presence of serum.

Its distinct mechanism of action makes it useful in treating infections caused by multiple drug-resistant bacteria. It is marketed in the United States under the trade name Cubicin by Cubist Pharmaceuticals. Customers also viewed :

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Product Details

Category Antibiotics & Antibacterials
Specialities
Price Enquire
CAS Number 103060-53-3
Formula C72H101N17O26
Molecular Weight 1620.67
Purity 96.0%
Appearance Light yellow to light beige powder
Availability Enquire
Storage Conditions -18°C
MSDS Data Sheet Click to download
MDL Number MFCD28968054
Harmonised Tariff 29419000

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