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Pranlukast brand name Onon, is a cysteinyl leukotriene receptor-1 antagonist. The cysteinyl leukotrienes (CysLT) LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of G protein-coupled receptors, CysLT1 and CysLT2. Pranlukast (ONO-1078) is a potent, selective and orally active cysteinyl leukotriene1 (CysLT1) receptor antagonist. Sold under the trade name Ultair, it was the first cysteinyl (peptidyl) leukotriene receptor antagonist (LTRA) marketed for the treatment of asthma.

Product Details

Category Asthma Research
Price POA
CAS Number 103177-37-3
Formula C27H23N5O4 · 0.5 H2O
Molecular Weight 490.51
Purity 98.0%
Appearance crystalline solid
Availability In Stock
Storage Conditions -18°C

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